andere Bezeichnungen
- Hirnkrebs
- Glioblastoma multiforme
Glioblastom
Das Glioblastom ist der häufigste bösartige hirneigene Tumor bei Erwachsenen. Das Glioblastom weist feingewebliche Ähnlichkeiten mit den Gliazellen des Gehirns auf und wird aufgrund der sehr schlechten Prognose nach der WHO-Klassifikation der Tumoren des zentralen Nervensystems als Grad IV eingestuft. Die Behandlung besteht in operativer Reduktion der Tumormasse, Bestrahlung und Chemotherapie.
Hauptwirksame Cannabinoide
- CBC
- CBD (Cannabidiol)
- CBDa
- CBDV
- CBG
- Δ⁹-THC
Studien/Artikel zur Behandlung von Glioblastom mit Cannabis-Medikation
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CannaTech 2017: Combating Epilepsy and Brain Cancer with Cannabinoids
- Cannabidiol enhances the inhibitory effects of delta9-tetrahydrocannabinol on human glioblastoma cell proliferation and survival.
- Antitumor effects of cannabidiol, a nonpsychoactive cannabinoid, on human glioma cell lines.
- Systematic review of the literature on clinical and experimental trials on the antitumor effects of cannabinoids in gliomas.
- Cannabidiol inhibits human glioma cell migration through a cannabinoid receptor-independent mechanism.
- Id-1 is a key transcriptional regulator of glioblastoma aggressiveness and a novel therapeutic target.
- Regulation of human glioblastoma cell death by combined treatment of cannabidiol, γ-radiation and small molecule inhibitors of cell signaling pathways.
- Triggering of the TRPV2 channel by cannabidiol sensitizes glioblastoma cells to cytotoxic chemotherapeutic agents.
- Cannabidiol, a non-psychoactive cannabinoid compound, inhibits proliferation and invasion in U87-MG and T98G glioma cells through a multitarget effect.
- Local delivery of cannabinoid-loaded microparticles inhibits tumor growth in a murine xenograft model of glioblastoma multiforme.
- Quantitative Analyses of Synergistic Responses between Cannabidiol and DNA-Damaging Agents on the Proliferation and Viability of Glioblastoma and Neural Progenitor Cells in Culture.
- Regulation of human glioblastoma cell death by combined treatment of cannabidiol, γ-radiation and small molecule inhibitors of cell signaling pathways.
- Regulation of human glioblastoma cell death by combined treatment of cannabidiol, γ-radiation and small molecule inhibitors of cell signaling pathways.
- Cannabinoids in Glioblastoma Therapy: New Applications for Old Drugs.
- Science/Human: Cannabis improved survival of patients with aggressive brain cancer in controlled clinical study
- Link Wikipedia (DE)